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Victims of Spanish wildfires killed while trying to escape along river bed ‘trap’

(CNN) — At least 12 people have been killed in one of southern Spain’s worst-ever wildfires, local officials said Friday, as tragic stories emerge of victims’ attempts to flee the inferno.

More than 460 emergency workers have been deployed to battle the fire near the town of Los Gallardos on Costa de Almería, Spanish Interior Minister Fernando Grande-Marlaska said Friday. At least 1,405 residents had been evacuated from their homes, said Antonio Sanz, the minister for health and emergencies in the region, which is popular among tourists.

“The most devastating fire to date in our region,” he said.

At least eight people are injured, four of them seriously, Grande-Marlaska said.

Andalusia’s regional leader Juanma Moreno said earlier Friday that at least 23 people were missing, but Grande-Marlaska later suggested those numbers were preliminary and that officials have received three official reports of missing people.

Temperature records have been smashed across Europe this summer as countries are hit by heat waves which are bringing extreme temperatures alarmingly early in the year. Firefighters are battling wildfires in Spain, Portugal and France.

Sanz said some victims attempted to escape the blaze via a dry river bed, which turned out to be a deadly “trap.” Four people died in a vehicle, while seven others were killed while trying to get away from the fire on foot, he said.

“Everything suggests that the victims were mostly, if not entirely, foreign nationals, though naturally this cannot be confirmed until their identities are officially established,” Sanz said.

Grande-Marlaska later confirmed that some of the dead were foreign nationals.

The mayor of Los Gallardos, Francisco Reyes, said the situation was “terrifying because there is a lot of wind and the fire has spread very quickly.”

“We have had to evacuate residents from Almocáizar and residents from Terminar de Vedas, and now we are heading towards the campsite because, as you can see, the wind is coming from the west and this is going to reach the campsite, where we also have 400 or 500 people,” he told Reuters news agency on Thursday.

Some relatives of missing people took to social media to share their concerns as authorities search for those unaccounted for, and seek to identify deceased victims.

A woman based in the United States posted on X that her brother was missing after trying to escape the fire through a valley with a group of 10 people. Meanwhile, another woman said on Facebook she had been unable to make contact with her parents after they said they were evacuating on Thursday.

Wildfires are not unusual in Europe, but the climate crisis is driving hotter, drier weather, which is setting the stage for fiercer fire seasons.

Speaking about Spain’s latest blaze, Fernando Ojeda, a professor in the Department of Biology at the University of Cádiz, said more than 3,000 hectares had been burned so far.

“That’s a massive amount. There have been bigger fires, but this covers a huge area. It’s not normal for fires of this scale to occur in Mediterranean landscapes,” Ojeda told Science Media Centre.

Record-breaking heat

Resident Jose Antonio Flores said the fire is a “disaster” for the environment and local people. “This is awful. A disaster, not just for the woodland, but for the people who have already died and everything that has happened. The house right there up above has burned completely,” he told Reuters.

The current death toll makes the blaze Spain’s deadliest wildfire since 2005, when ​11 firefighters were killed in the central province of Guadalajara after a fire was sparked by a barbecue, Reuters reported.

Last month, Spain set national records with temperatures on some days reaching 12.8 degrees Fahrenheit (7.1 Celsius) above average, according to the national weather service AEMET.

France and the UK also set record temperatures last month amid the unprecedented heat, with many French towns and cities facing temperatures above 104 degrees Fahrenheit (40 Celsius).

Spain’s meteorological office issued more high temperature warnings in recent days for parts of the Andalusia region. Video released by authorities shows firefighters battling large flames engulfing vegetation in the area.

Meanwhile, emergency services have been tackling blazes in neighboring France too, with thousands of hectares of land burned near the border with Spain, according to local authorities.

In Portugal, recent wildfires have caused plumes of smoke so large they could be seen from space, according to the European Union.

Europe is the world’s fastest-warming continent, with temperatures increasing more than twice as fast as the global average, according to the EU’s Copernicus Climate Change Service.

Spanish Prime Minister Pedro Sánchez expressed his sadness over the recent deaths in the country’s south. “I want to convey my condolences to the families of those who died,” he said on X.

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Personalized mRNA cancer vaccine shows promise in extending lifespan in melanoma trial

Stock photo of a doctor examining a patient's skin. (Lordhenrivoton/STOCK PHOTO/Getty Images)(NEW YORK) -- Merck and Moderna announced Wednesday that a personalized mRNA-based cancer vaccine succeeded in a large, late-stage trial among high-risk patients with melanoma.The individualized vaccine, when paired with the existing immunotherapy, Keytruda, is the first and only combination regimen that demonstrated success in potentially extending melanoma patients' lifespans.In Phase 3 trials, the regimen significantly reduced the risk of cancer returning or spreading. The trial was conducted among patients whose high-risk melanoma had been surgically removed.The combination treatment regimen pairs the personalized vaccine with Merck's Keytruda, which had previously been used to treat the cancer alone.The treatment showed a 49% reduction of melanoma return after patients underwent surgery and a 59% reduction of metastasization of the cancer to distant organs.Key questions surrounding regulatory review of the vaccine remain.The Food and Drug Administration has not yet approved the vaccine. The agency will review the full data once it has been collected and submitted.While the FDA has already approved other cancer vaccines, this new treatment represents a step forward in the field as it uses mRNA technology and personalized treatment for each patient.Merck and Moderna plan to present data at an upcoming international medical meeting where they hope to engage regulators on filing submissions for approval of the regimen, the companies said in a joint press release.Dr. Ahmad Tarhini, an oncologist at the H. Lee Moffitt Cancer Center & Research Institute, told ABC News that he expects the treatment to be approved based on very positive trial results and made available to patients likely by early 2027.The vaccine uses genetic information from patients' individual tumors to identify and attack the cancer."It's what we call individualized neoantigen therapy, where we take the cancer itself, we do genetic sequencing and try to define a unique mutational fingerprint of the cancer itself," Tarhini said.Melanoma is the deadliest form of skin cancer, with about 112,000 new cases expected in 2026, according to the American Cancer Society.The treatment is considered relatively safe, according to the companies. The most common side effects include fatigue, sore arm and chills.Treatments utilizing mRNA technologies are being used in trials for other forms of cancer, including that of the bladder, kidney, lungs, stomach and pancreas, according to Tarhini."I think it will certainly improve the outcome of our patients," Tarhini said. "We are, you know, excited about this development. My expectation is this will eventually change the standard care of our patients."Copyright © 2026, ABC Audio. All rights reserved.
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