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Record number of West Nile virus cases since 2004, CDC warns ahead of holiday weekend

A Culex mosquito, primary vectors for several viral and parasitic diseases inside a house in Tehatta, West Bengal, India, March 3, 2026. (Soumyabrata Roy/NurPhoto via Getty Images)

(NEW YORK) — A record number of West Nile virus cases have been recorded for this time of year, the Centers for Disease Control and Prevention (CDC) warned on Wednesday ahead of the upcoming holiday weekend.

At least 48 cases of West Nile have been reported so far this year compared to an average of 10 typically by the end of June. This is the highest number of infections reported at this point in year since 2004, according to the federal health agency.

Additionally, at least 23 states are reporting West Nile activity, which is the highest number recorded over the last 10 years, CDC data shows.

The illness is the leading cause of mosquito-borne disease in the contagious U.S., with several thousand cases and over 100 deaths reported on average each year.

With millions gathering outside for Fourth of July, the CDC is urging Americans to take precautions and reduce their risk of mosquito bites.

Since 1999, the disease has killed more than 3,300 Americans. Cases have historically peaked in August and are mostly reported from June through October.

While many people infected do not develop symptoms, about one in five do. Symptoms include fever, headache, body aches, vomiting, diarrhea or rash, according to the CDC.  Most symptoms soon disappear, though weakness and fatigue may last for weeks or months.

Fewer than 1% of people infected develop severe illness that affects the central nervous system, including inflammation of the brain (encephalitis) and the membranes around the brain and spinal cord (meningitis), the CDC says.

Risk of severe disease, hospitalization and death increase with older age; certain medical conditions including cancer, high blood pressure and kidney disease; and a weakened immune system.

There are currently no vaccines for West Nile virus, nor disease-specific treatments. The CDC recommends rest, fluids and over-the-counter medications to treat the infection. Those with severe illness may need to be hospitalized and receive additional support treatments, such as intravenous fluids.

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CIA director makes unannounced visit to Moscow to meet with Russian officials, source says

(CNN) — CIA Director John Ratcliffe traveled to Moscow overnight to meet with Russian officials, a US official familiar with his travel told CNN.The official declined to share the substance of the meetings or the topics set to be discussed. The CIA declined to comment.The US asked Ukraine to halt drone and missile strikes in Moscow and other cities in the north of Russia ahead of Ratcliffe’s trip, a person familiar with the matter said. The request was for Monday through Wednesday of this week. The Ukrainians were told a senior US official would be traveling in Russia.The visit is Ratcliffe’s first known trip to Russia as CIA director under President Donald Trump. It comes as negotiations to end the war between Russia and Ukraine have stalled.The CIA director had no plans to meet with Russian President Vladimir Putin during his trip, Kremlin spokesperson Dmitry Peskov told state media TASS on Wednesday morning .Ratcliffe’s visit also comes one day after Treasury Secretary Scott Bessent announced “Operation Economic Outcast” — a new strategy designed to isolate Iran from the rest of the world by punishing countries and entities that continue to do business with Tehran. Russia is a strategic trading partner with Iran.Early Tuesday morning, a military transport aircraft — an American Boeing C-17 Globemaster III — landed at Moscow’s Vnukovo International Airport, according to flight tracking website Flightradar24. It appeared the flight had initially taken off from Joint Base Andrews in Maryland.A spokesperson for Latvia’s Defense Ministry said the flight — which left from Riga, the Latvian capital — was “properly coordinated and authorized for operation within the airspace.”“Since the aircraft is not operated by the National Armed Forces of Latvia, we are unable to provide any further information concerning this particular flight,” the spokesperson told CNN.CBS News was first to report on Ratcliffe’s presence in Russia.This story has been updated with additional information.The-CNN-Wire™ & © 2026 Cable News Network, Inc., a Warner Bros. Discovery Company. All rights reserved.
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